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Kombiglyze Xr 5/1000mg Tab
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Marketer
Astrazeneca Pharma India Ltd
Composition
Saxagliptin (5mg) + Metformin (1000mg)
100% Genuine Products
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Fully Sanitized Packing
About Kombiglyze Xr 5/1000mg Tab
Saxagliptin/Metformin is a combination medication used to treat type 2 diabetes. It works by improving insulin secretion and reducing glucose production. Common side effects include gastrointestinal issues. It's crucial to follow your doctor's instructions regarding dosage and to report any unusual symptoms immediately. Safety considerations include alcohol consumption, driving, pregnancy, and kidney/liver function.
Ingredients of Kombiglyze Xr 5/1000mg Tab

    Saxagliptin

    A dipeptidyl peptidase-4 (dpp-4) inhibitor that helps the body release more insulin when blood sugar is high and reduces the amount of glucose the liver produces.

    Metformin

    A biguanide that works in several ways to lower blood sugar, including reducing glucose production by the liver and improving insulin sensitivity.

Direction for Use of Kombiglyze Xr 5/1000mg Tab

    Treatment of type 2 diabetes mellitus in adults, especially those who did not achieve adequate glycemic control with metformin alone.

How Kombiglyze Xr 5/1000mg Tab Works

Saxagliptin inhibits DPP-4, an enzyme that breaks down incretins (hormones that stimulate insulin release). This leads to increased insulin secretion and decreased glucagon secretion, ultimately lowering blood glucose levels. Metformin reduces hepatic glucose production, enhances insulin sensitivity, and improves glucose uptake by peripheral tissues.

Storage and Handling of Kombiglyze Xr 5/1000mg Tab

Store at room temperature (68-77°F or 20-25°C). Protect from moisture and light. Keep out of reach of children.

Dosage of Kombiglyze Xr 5/1000mg Tab

    Dosage should be determined by a healthcare professional based on individual needs and response.

    It's typically started at a lower dose and gradually increased as tolerated.

    Take with food to reduce gastrointestinal side effects.

Side effects of Kombiglyze Xr 5/1000mg Tab

Rare but serious side effects include lactic acidosis (a build-up of lactic acid in the blood), pancreatitis, and allergic reactions.

    Common side effects may include nausea, vomiting, diarrhea, constipation, abdominal pain, headache, dizziness, upper respiratory tract infection.

Safety Consideration or Warnings
    Alcohol Consumption

    Limit alcohol intake as it can increase the risk of lactic acidosis.

    While Driving or Operating Machinery

    May cause dizziness or lightheadedness. Avoid driving or operating machinery if affected.

    Pregnant & Breastfeeding Women

    Use is generally not recommended during pregnancy or breastfeeding. Consult your doctor.

    Children

    Not approved for use in children.

    Kidney

    Dose adjustment may be necessary for those with kidney problems.

    Liver

    Dose adjustment may be necessary for those with liver problems.

References

    Consult your doctor or pharmacist for detailed information and references.

    Check the official prescribing information for the specific brand of Saxagliptin/Metformin you are taking.

Last Updated On 26 Jun. 2025 | 03:08 AM (IST)
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