Prescription Required.
Propofol is the active ingredient in propofol formulations. It is a short-acting intravenous anesthetic that belongs to the class of drugs known as general anesthetics.Propofol formulations may also contain inactive ingredients like soybean oil, glycerol, and egg lecithin, which help to stabilize and deliver the medication.
Propofol is primarily used for general anesthesia during surgery or procedures.
It can also be used for sedation in intensive care units (ICUs) for critically ill patients.
In some cases, it may be used for the induction of anesthesia in patients undergoing certain procedures.
Propofol works by enhancing the effects of the neurotransmitter GABA (gamma-aminobutyric acid) in the brain. This action leads to a decrease in neuronal activity, resulting in sedation and unconsciousness.
Propofol formulations are typically stored in a refrigerator at temperatures between 2°C and 8°C (36°F and 46°F).
It is important to protect the medication from light and freezing.
Once opened, propofol formulations should be used within a specific time frame, which varies depending on the specific product. Consult the product label for the recommended usage period.
Propofol should only be administered by a qualified healthcare professional.
The dosage of propofol varies depending on the patient's age, weight, medical condition, and the type of procedure or sedation being performed.
Propofol is typically administered intravenously by a healthcare professional.
The rate of infusion is adjusted to achieve the desired level of sedation or anesthesia.
Common side effects of propofol include:
In rare cases, more serious side effects may occur, including:
Pain at the injection site
Nausea
Vomiting
Low blood pressure
Slow heartbeat
Breathing difficulties
Confusion
Dizziness
Drowsiness
Allergic reactions
Seizures
Coma
Cardiac arrest
Alcohol consumption can increase the risk of side effects from propofol. It is important to inform your doctor about any alcohol use before receiving propofol.
Propofol can cause drowsiness and dizziness. Do not drive or operate machinery for at least 24 hours after receiving propofol.
Propofol should only be used during pregnancy if the potential benefits outweigh the risks to the mother and fetus. It is not recommended for use during breastfeeding.
Propofol is not typically used in children under the age of 1 month, and careful consideration should be given to its use in children under the age of 2 years.
Propofol is metabolized by the liver, and its elimination may be affected in patients with impaired liver function. It is important to inform your doctor about any kidney or liver problems before receiving propofol.
https://www.fda.gov/drugs/drug-safety-and-availability/propofol-important-safety-information
https://www.mayoclinic.org/drugs-supplements/propofol-injection-route/description/drg-20067732
https://www.ncbi.nlm.nih.gov/pubmed/12740153
