Is a synthetic progestogen, a type of hormone similar to progesterone naturally produced in the body.
Treatment of dysfunctional uterine bleeding (DUB)
Hormone replacement therapy (HRT) in women with estrogen deficiency who experience breakthrough bleeding or spotting
Emergency contraception (when taken within 72 hours of unprotected sex)
Management of endometriosis (though typically used alongside other treatments)
Amenorrhea (absence of menstruation)
Premenstrual syndrome (PMS), although not as a firstline treatment
Hyston Sr 10mg Tab (Norethisterone) works primarily by suppressing the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. This in turn reduces the production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary gland, which then leads to decreased ovarian stimulation and reduced endometrial growth. In high doses, it also directly affects the endometrium, making it less receptive to implantation.
Store in a cool, dry place away from direct sunlight and heat. Keep out of reach of children. Check the expiration date on the packaging.
Dosage varies greatly depending on the specific indication and patient's medical history. Always follow the prescription provided by your doctor.
Norethisterone is usually administered orally (as tablets).
Breast tenderness
Headache
Weight changes (gain or loss)
Mood changes (irritability, depression)
Nausea
Fluid retention
Breakthrough bleeding (especially in HRT)
Acne
Changes in libido
Alcohol may interact with norethisterone or other medications taken concurrently. Consult your doctor.
Drowsiness or dizziness may occur; avoid driving or operating machinery if affected.
Generally contraindicated during pregnancy unless under strict medical supervision; should be avoided during breastfeeding due to potential transfer to the infant through breast milk.
Not typically used in children except in specific circumstances under a doctor's supervision.
May need dosage adjustment in patients with severe renal impairment. Consult your doctor.
May need dosage adjustment in patients with severe hepatic impairment. Consult your doctor.
Refer to your doctor's prescription and patient information leaflet.
Reputable medical databases like UpToDate and PubMed
